Allograft Safety


Testing donated tissues in the laboratory to ensure donor tissues are free from disease and are suitable for transplantation. The following information provides a background on the approach.

To learn more about the various certifications of Bone Bank Allografts and Texas Human Biologics, please click here.

Laboratory Testing


In accordance with FDA Standards, donor specimens are collected and sent to an independent laboratory certified under the Clinical Laboratory Improvement Amendments of 1988 (CLIA) to test for the following infectious diseases and antibody or antigen markers listed below:

Human Immunodeficiency Virus Type I Ab
HIV I Antibody
HIV I Nucleic Acid Test
Human Immunodeficiency Virus Type II Ab
HIV II Antibody
Human T-Lymphotrophic Virus Type I
HTLV I Antibody
Human T-Lymphotrophic Virus Type II
HTLV II Antibody
Hepatitis B Virus
HBc Antibody (total)
HBs Antigen
Hepatitis C Virus
HCV Antibody
HCV Nucleic Acid Test
Rapid Plasma Reagin Test
FTA Confirmation

All donors are evaluated for hemodilution which could potentially affect test results. Only a licensed physician determines final donor suitability.